Patients who decide to use the services of a donor sperm bank are usually interested in how potential donors are selected and examined. Before the donor is included in the sperm bank, he undergoes an extended medical and genetic examination. He must be examined for HIV infection, syphilis, hepatitis B and C and a number of sexually transmitted diseases (gonorrhea, chlamydia, cytomegalovirus, herpes, ureaplasmosis, mycoplasmosis). The donor is examined by a therapist, a urologist, medical and genetic counseling, and additional genetic research (karyotyping, cystic fibrosis and AZF factor testing). In addition, the donor must be consulted by a psychiatrist.
Donor sperm is frozen and stored for six months (the so-called "quarantine"), after which the donor is re-examined for HIV infection, syphilis and hepatitis, since these diseases can be detected only a few months after infection (penetration of the pathogen into the body). The use of thawed donor sperm is allowed only after receiving repeated negative test results from the donor after 6 months.