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Surrogacy
Surrogacy is a therapeutic method in which embryos obtained in the IVF cycle are transferred to the uterus of a woman who is not genetically related to the embryos she is carrying. In the surrogacy cycle, the eggs of an infertile woman are fertilized with her husband’s sperm and transferred to the uterus of the surrogate mother. Surrogacy is the most difficult IVF program. The involvement of a third person in the birth of a child, which became possible as a result of the almost fantastic progress of medical science, made it possible for women whose infertility had previously been insurmountable to experience the joy of motherhood.
In which case do patients require surrogacy? The most common cause is the absence of a uterus. The uterus may be missing from birth (Rakitansky-Kustner syndrome) or surgically removed (hysterectomy for vital reasons, for example, with extensive bleeding during cesarean section). Other groups of patients who are indicated for surrogacy include women with an increased risk of miscarriage, with diseases in which pregnancy and childbirth are contraindicated (for example, severe heart disease), and those who have had numerous unsuccessful attempts at in vitro fertilization (IVF) for unexplained reasons.
Surrogacy is based on the same principles as in cycles using donor eggs. A woman who receives eggs undergoes an IVF cycle. At the same time, the surrogate mother’s uterus is being prepared for implantation with estrogen and progesterone preparations. The eggs are extracted during an outpatient procedure under light anesthesia. The eggs are fertilized with the sperm of the patient’s husband and cultured for several days. On the day of transfer, the embryos with the highest implantation potential are placed in the uterine cavity of the surrogate mother. The number of transferred embryos depends on the age of the woman from whom the eggs were obtained and on the quality of the embryos obtained.

The percentage of pregnancy in cycles with surrogacy mainly depends on the age of the woman from whom the eggs were obtained. In cases where donor eggs and a surrogate mother are used, that is, when the quality of the eggs and the condition of the uterus are optimal, the effectiveness of treatment is the highest in modern reproductive medicine, reaching 70−75%.
A woman who decides to become a surrogate mother may do so for humane reasons. This may be a relative or a close friend of an infertile couple. Many people go to surrogacy for financial reasons — they receive a financial reward for carrying a child. According to Armenian law, a surrogate mother must be at least 35 years old and have at least one child.
Before carrying out the in vitro fertilization (IVF) program, the genetic parents and the surrogate mother conclude a notarized contract in which they stipulate the terms of remuneration and registration of the newborn.
  1. Absence of uterus (congenital or acquired);
  2. Deformity of the uterine cavity or cervix in congenital malformations or as a result of diseases;
  3. Adhesions of the uterine cavity that are not amenable to therapy;
  4. Extragenital and genital pathology in which pregnancy is contraindicated or impossible;
  5. Unsuccessful repeated IVF attempts with repeated receipt of high-quality embryos, the transfer of which does not lead to pregnancy.
Indications for IVF in the surrogacy program are:
Requirements for surrogate mothers:
  • physical and mental health,
  • age from 18 to 35 years inclusive,
  • having a healthy child of your own.
Stages of the surrogacy program:
  1. Synchronization of the surrogate and genetic mother's menstrual cycles using GnRH agonists or oral contraceptives.
  2. Preparation of the surrogate mother's endometrium with estrogen and progesterone preparations.
  3. Stimulation of ovulation of the genetic mother using gonadotropins.
  4. Puncture of the ovaries of the genetic mother, fertilization of the resulting eggs with the sperm of her husband (donor).
  5. Transfer of embryos into the uterine cavity of a surrogate mother.